Periodontal diseases
Conditions
Interventions
Test group:Use an experimental toothpaste containing ganoderma lucidum and saffron extract
Control group :Use a control toothpaste that does not contain ganoderma lucidum and saffron extract
Sponsors
Peking University Hospital of Stomatology
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Good general health, with no uncontrolled systemic diseases; 2. Male or female,18-60 years old; 3. More than 20 healthy natural teeth; 4. Modified Quigley-Hein plaque index >=1.5; 5. Loe-Silness Gingival index >=1.0, bleeding index >=1.0 or (BOP% >=50%); 6. Sign the informed consent form, comply with the trial rules and requirements, and be able to complete the 3.5 month clinical trial.
Exclusion criteria
Exclusion criteria: 1. Currently participating in clinical trials of other stomatological clinical trials; 2. Currently pregnant, breastfeeding, or have pregnancy plans during the test cycle; 3. The presence of the following oral diseases: unfilled caries, large area of restorations in the neck of the tooth, more than 6 severe staining counts on the tooth surface, severe gingival receding, severe periodontal disease, oral mucosal disease, and oral tumors; 4. Received periodontal therapy within 6 months before the trial; 5. Wear full mouth or removable partial denture or orthodontic appliance; 6. Used antibacterial drugs or mouthwash within one month before the trial; 7. Allergic to any component of the investigational product; 8. The researchers believe that their general or oral condition is not suitable for participation in this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change of the bleeding index;Change of plaque index; | — |
Secondary
| Measure | Time frame |
|---|---|
| change of the bleeding index;Change of gingival index;Change of plaque index; | — |
Countries
China
Contacts
Public ContactXiaopei Chi
Peking University Hospital of Stomatology
Outcome results
None listed