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Efficacy of Oliceridine for Postoperative Analgesia in Patients Undergoing Abdominal Surgery: A Comparative Analysis with Oxycodone

Efficacy of Oliceridine for Postoperative Analgesia in Patients Undergoing Abdominal Surgery: A Comparative Analysis with Oxycodone

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500099782
Enrollment
Unknown
Registered
2025-03-28
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain

Interventions

Group G:Oliceridine postoperative analgesia
Group O:Oxycodone postoperative analgesia

Sponsors

Xi'an International Medical Center Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age > 18 years old; 2. Provide written informed consent and voluntarily agree to receive postoperative patient-controlled intravenous analgesia (PCIA) treatment; 3. Undergo elective abdominal surgery, including operations on the stomach, intestines, liver, gallbladder, appendix, kidney, ureter, or bladder; 4. Be classified as American Society of Anesthesiologists (ASA) physical status I to III; 5. Have a body mass index (BMI) between 18 and 30 kg/m^2; 6.The anticipated duration of surgery is between 1 and 5 hours.

Exclusion criteria

Exclusion criteria: 1. Patients with known contraindications or hypersensitivity to µ-opioid agonists, hydrochloride oxycodone, or any other components of the medication; 2. Patients with a history of chronic pain and its management; 3. Patients with a history of difficult airway management or delayed extubation; 4. Patients with severe hepatic or renal impairment; 5. Patients with psychiatric disorders; 6. Patients requiring emergency surgery or secondary emergency procedures; 7.Pregnant and lactating women .

Design outcomes

Primary

MeasureTime frame
Postoperation NRS Score;

Countries

China

Contacts

Public ContactYu Guo

Xi'an International Medical Center Hospital

guoyu986121@163.com+86 139 0929 9052

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026