postoperative nausea and vomiting
Conditions
Interventions
the bundle care PONV management strategy group (Group B):Prior to the induction of anesthesia, intravenous administration of dexamethasone (5 mg) will be initiated. Intraoperative anesthesia was maint
Intravenous injection of the antiemetic 5-hydroxytryptamine receptor antagonist ondansetron (8 mg) will be administered before the conclusion of surgery.
Control group(Group C):Intraoperative anesthesia was maintained with inhaled sevoflurane and remifentanil. Intravenous injection of the antiemetic 5-hydroxytryptamine receptor antagonist ondansetron (
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
14 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients proposed for laparoscopic cholecystectomy at the West China Hospital of Sichuan University; 2. Patients with an American Society of Anesthesiologists (ASA) grade of I to II; 3. Patients between the ages of 18 and 65 years.
Exclusion criteria
Exclusion criteria: 1. Pregnancy, steroid therapy; 2. Uncontrolled diabetes mellitus (glycated hemoglobin > 8%); 3. The use of opioids, sedatives or any analgesic within the week prior to surgery; 4. History of alcohol or drug abuse; 5. Preoperative diagnosis of acute cholecystitis, acute pancreatitis, choledochal stone or gallbladder cancer;Laparoscopic intermediate open surgery patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative nausea and vomiting (PONV) ; | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative pain; | — |
Countries
China
Contacts
Public ContactLuo Zhen
West China Hospital, Sichuan University
Outcome results
None listed