Elderly patients undergoing painless gastroscopy or treatment for gastric diseases
Conditions
Interventions
Control group:Propofol 1.5-2 mg/ kg + alfentanil 10ug/kg
Experimental Group:Dexmedetomidine 0.6 ug/kg + alfentanil 10 ug/kg
Sponsors
Shiyan City People's Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1: The age range was 65 to 80 years old; 2: ASA grade II-III; 3: Patients who voluntarily underwent gastroscopy and agreed to sedation/anesthesia.
Exclusion criteria
Exclusion criteria: 1:Patients with contraindications of digestive endoscopy and refusal of anesthesia; 2:Patients with ASA grade >III; 3:Patients with a history of allergy to anesthetic drugs; 4:Patients with a history of long-term use of sedative and analgesic drugs; 5:Patients with a history of neuropsychiatric disorders and severe cardiopulmonary diseases; 6:Patients with acute respiratory infection, difficult airway, preoperative hypoxemia (SPO250 beats/min), degree II or above atrioventricular block, hypotension (SBP180mmHg, DBP>110mmHg); 8:Patients with acute gastrointestinal bleeding, liver and kidney dysfunction, gastrointestinal obstruction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of Respiratory Depression; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean Arterial Pressure;Heart Rate;Total anesthesia duration;Endoscopy Procedure Time;Total time in the exam room;Intraoperative Complication Spectrum; | — |
Countries
China
Contacts
Public ContactZheng Min
Shiyan City People's Hospital
Outcome results
None listed