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Determination of the median effective dose (ED50) of Ciprofol for successful sedation in pediatric patients during general anesthesia induction

Determination of the median effective dose (ED50) of Ciprofol for successful sedation in pediatric patients during general anesthesia induction

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500099738
Enrollment
Unknown
Registered
2025-03-27
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Sponsors

Weifang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1. Elective surgery; 2.Aged 3-12 years, regardless of gender; 3. Mechanical ventilation with a laryngeal mask or tracheal intubation; 4. ASA class I-II;

Exclusion criteria

Exclusion criteria: 1 American Society of Anesthesiologists ( ASA ) grade >= III ; 2 body mass index >= 28 kg / m^2 ; 3 unable to cooperate with intravenous induction ; 4 Difficult airway ; 5 may be allergic to the related drugs in this study ; 6 Mental and nervous system development retardation ; 7 Patients who received sedation / anesthesia 24 hours before anesthesia induction.

Design outcomes

Primary

MeasureTime frame
Mask acceptance of children after induction;Eyelash reflex disappears;Amplitude of body movement;

Secondary

MeasureTime frame
General information: gender, age, body mass index (BMI), ASA grading etc; Hemodynamic changes before and after induction;

Countries

China

Contacts

Public ContactPeihe Nie

Weifang People's Hospital

peihenie@126.com+86 187 6461 9226

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026