growth retardation in children
Conditions
Interventions
Observation group:None
Sponsors
The First Affiliated Hospital of Hebei North University
Eligibility
Sex/Gender
All
Age
3 Years to 10 Years
Inclusion criteria
Inclusion criteria: 1.Persons whose height is less than 1 SD below the median value of the reference population of the same age and sex; 2. Children between the ages of 3 (minimum age) and 10 (maximum age) male and female; 3. No previous growth hormone therapy; 4. Informed consent form signed by the child/subject's parent/legal guardian is obtained; 5. The child/subject's parent/legal guardian is able to communicate well with the investigator.
Exclusion criteria
Exclusion criteria: 1. The presence of diseases that affect the growth and development of children including but not limited to abnormal thyroid function abnormal parathyroid function growth hormone deficiency idiopathic dwarfism; 2. The presence of a disease that affects the child's standing or height measurement including but not limited to rickets scoliosis kyphosis; 3. Presence of serious systemic diseases such as severe cardiac pulmonary hepatic and renal insufficiency severe endocrine system diseases severe central nervous system and blood diseases; 4. Previous treatment with drugs that may interfere with growth hormone secretion or growth hormone action; 5. Known or suspected hypersensitivity to the investigational drug or related medications 6. The presence of overweight which was determined by BMI: children under 7 years of age with a BMI of +1SD and above were considered overweight; children over 7 years of age with a BMI greater than or equal to the age-specific threshold were considered overweight; 7. The investigator determines that the subject or parent/legal guardian is likely to be non-compliant with the implementation of the study; 8. Those whom the investigator deems unsuitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in diet;BMI(mean change value, improvement rate, recurrence rate);Height (mean change value improvement rate recurrence rate); | — |
Countries
China
Contacts
Public ContactLiu Zhenkui
The First Affiliated Hospital of Hebei North University
Outcome results
None listed