Embryonic aneuploidy rate and pregnancy outcome
Conditions
Interventions
Low level AMH group(0-25th percentile):none
Moderate level AMH group(25th-75th percentile):none
High level AMH group(75th-100th percentile):none
Sponsors
General Hospital of the Northern Theater of Operations, People's Liberation Army, China
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1 . female, 20=50 years; 2. repeated miscarriages (>=2 spontaneous miscarriages); 3. repeated transfer failures (>=3 transfers or cumulative transfers of >= 4-6 high-quality embryos or>=3 highly rated blastocysts still not implanted); fulfillment of 1 is required to satisfy any of 2 and 3 at the same time
Exclusion criteria
Exclusion criteria: 1. chromosomal abnormalities in either spouse; 2. abnormalities in the uterine cavity (e.g., fibroids pressing on the uterine cavity, endometrial polyps, etc.); 3. endocrine or autoimmune diseases (e.g., diabetes, systemic lupus erythematosus, etc.); 4. severe dyspareunia in the male partner; and 5. missing data from the core of the medical record.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| embryonic aneuploidy rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical pregnancy rate;Early abortion rate; | — |
Countries
China
Contacts
Public ContactYuexin Yu
General Hospital of the Northern Theater of Operations, People's Liberation Army, China
Outcome results
None listed