Renal tumor
Conditions
Interventions
Observation group:None
Sponsors
Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-75 years old, male or female; 2. High-risk non-metastatic renal cell carcinoma diagnosed by biopsy pathology and neoadjuvant therapy is required; 3. Have not received tumor-related treatments including radiotherapy, chemotherapy, targeted therapy, and immunotherapy in the past; 4. Fresh specimens of sufficient cell culture can be obtained from conventional diagnosis and treatment protocols; 5. No previous diagnosis of other malignant tumors, or diagnosis of malignant tumors, but the prognosis is good, such as basal cell carcinoma of the skin; 6. ECOG physical performance status less than or equal to 2; 7. Have at least 1 measurable lesion (according to RECIST1.1); 8. Voluntarily join this study, sign the informed consent form, have good compliance and be willing to cooperate with the follow-up.
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating women; 2. Severe comorbid diseases that will interfere with the treatment plan; 3. Allergy to the target target or immunopharmaceutical components; 4. Cognitive impairment, mental disorders, poor compliance; 5. Other circumstances judged by the investigator to be inappropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Results of in vitro PTC test;Objective response rate;Adverse events of patients during drug treatment;Vital signs;Laboratory indices; | — |
Secondary
| Measure | Time frame |
|---|---|
| R0 resection rate;Pathological complete response;Progression-free survival;Overall survival; | — |
Countries
China
Contacts
Public ContactQingbo Huang
Chinese PLA General Hospital
Outcome results
None listed