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Prevention of post-thyroidectomy scars with onion extract preparations combined with PDL laser: A prospective randomized controlled trial

Prevention of post-thyroidectomy scars with onion extract preparations combined with PDL laser: A prospective randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500099683
Enrollment
Unknown
Registered
2025-03-27
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Scar formation

Interventions

Group A:After removing the stitching 1 week after operation, the onion extract preparation was evenly applied to the incision of traditional thyroid surgery, and gently massaged with fingers until the
Group B:After removing the stitching 1 week after operation, the onion extract preparation was evenly applied to the incision of traditional thyroid surgery, and gently massaged with fingers until the

Sponsors

The First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1. Willing to sign the informed consent; 2. The surgical method was traditional transcervical thyroidectomy, the surgical incision was clean incision, no wound infection, using the same surgical suture and absorbable suture, the incision was well synched; 3. Age 18-55 years old (including boundary value), regardless of gender; 4. Thyroid benign tumor or thyroid malignant tumor stage ?; 5. The wound healed well after thyroid tumor operation, and the fresh scar after suture removal was needed in the neck one week after operation. 6. Normal preoperative laboratory indicators: (1) White blood cell count >=3.5×10^9 g/L; (2) Platelet >=125×10^9 /L; (3) Hemoglobin >=130g/L; (4) ALT =90mL/ (min*1.73?); (8) Normal coagulation function;

Exclusion criteria

Exclusion criteria: 1. Keloid patients; 2. Metal implants in the treatment area; 3. Oral retinoic acid within 6 months or chemical peeling (chemical peeling); 4. Onion extract and photoelectric allergy; 5. inflammation in the treatment area; 6. patients requiring postoperative chemotherapy or 131I therapy 7. Patients with autoimmune diseases such as rheumatism, systemic lupus erythematosus and mental diseases; 8. Patients with long-term use of hormones, immunosuppressants or antineoplastic drugs; 9. Angina pectoris, myocardial infarction, arrhythmia and other heart diseases; 10. patients with hypertension and diabetes; 11. Patients with abnormal liver and kidney function, abnormal coagulation function, and systemic bacterial or fungal infection; 12. Cerebral infarction and cerebral hemorrhage occurred in this case. 13. Pregnant or lactating women or patients with a recent history of major surgery; 14. The physician had poor obedience and an impatient personality, and could not wait for the interval time or demand a quick effect. 15. The same patient was treated with other treatment methods during treatment. 16. The absence of standardized photos or follow-up records of patients will affect the efficacy and safety evaluation. 17. You patient's standardized photos due to light, posture and other reasons affect the accurate evaluation of efficacy analysis; 18. The investigators considered that they were not suitable to participate in this study.

Design outcomes

Primary

MeasureTime frame
Vancouver Scar Assessment Scale;Subjective Scar Assessment ;Ultrasound shear wave elastography;Optical coherence tomography angiography;

Countries

China

Contacts

Public ContactChen Xulin

High-tech District, the First Affiliated Hospital of Anhui Medical University

okcxl@126.com+86 138 6615 1972

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026