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Comparative Study of Trabeculotome tunnelling trabeculoplasty (3T) versus Gonioscopy-Assisted Trabeculectomy (GATT) for the Treatment of Primary Open-Angle Glaucoma

Comparative Study of Trabeculotome tunnelling trabeculoplasty (3T) versus Gonioscopy-Assisted Trabeculectomy (GATT) for the Treatment of Primary Open-Angle Glaucoma

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500099671
Enrollment
Unknown
Registered
2025-03-27
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Open-Angle Glaucoma

Interventions

The group of 3T:3T Surgery
The group of GATT:GATT Surgery

Sponsors

Ophthalmology Department, Chengdu First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Age range: 18 to 75 years old, regardless of gender; (2) Patients with Primary Open-Angle Glaucoma (POAG) who have intraocular pressure (IOP) > 21 mmHg despite maximum tolerated medical therapy for lowering IOP and have indications for glaucoma surgery; (3) No history of glaucoma surgery or previous surgery that did not compromise the Schlemm's canal; (4) Voluntary acceptance of surgery and ability to cooperate with all preoperative and postoperative examinations. Patients must meet all these criteria to be eligible for surgery.

Exclusion criteria

Exclusion criteria: (1) Patients with a history of ocular trauma or surgery that may compromise the integrity of the Schlemm's canal; (2) Patients with corneal opacity precluding visualization of the anterior chamber angle structures, as well as those with abnormal anterior chamber angle structures; (3) Patients with severe heart disease, lung disease, advanced cancer, or other conditions that preclude tolerance to ophthalmic surgery; (4) Patients who fail to complete all preoperative and postoperative examinations; (5) Pregnant or lactating women; (6) Other patients deemed ineligible by the investigator for any reason. Patients meeting any of the above criteria are excluded from the study.

Design outcomes

Primary

MeasureTime frame
Intraocular pressure (IOP);The quantity and types of anti-glaucoma medications.;visual acuity;visual field;complication;

Secondary

MeasureTime frame
The status of postoperative interventions (including secondary anti-glaucoma surgery).;Collection of adverse events;gonioscopy grading;

Countries

China

Contacts

Public ContactLiuzhi-Zeng

Ophthalmology Department, Chengdu First People's Hospital

676681961@qq.com+86 180 1139 0117

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026