diabetes mellitus
Conditions
Interventions
DM group:No intervention
MCI control group:Take 10g/day of maltodextrin for 24 weeks
MCI Experimental Group :Take 20g of resistant dextrin per day for 24 weeks
Sponsors
The Second Hospital of Shandong University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age between 40 and 80 years old; 2. Meet the diagnostic criteria for type 2 diabetes; 3. Course of diabetes >= 5 years; 4. Stable blood glucose control; 5. Regularly taking hypoglycemic drugs or using insulin; 6. Dietary habits.
Exclusion criteria
Exclusion criteria: 1. Severe heart, liver, and kidney dysfunction exists; 2. History of mental illness; 3. History of severe cerebrovascular disease; 4. Family history of cognitive impairment; 5. I am currently taking medication that affects cognitive function; 6. Frequent adjustment of hypoglycemic drugs; 7. Irregular diet, complex and varied recipes; 8. History of intestinal surgery or inflammatory bowel disease; 9. Complicated with tumor, infection, severe anemia or acute complications of diabetes; 10. Alcohol abuse; 11. The patient has severe hearing or vision loss; 12. Illiteracy;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive Function ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood routine;Liver function;Renal function;Blood sugar;Glycosylated hemoglobin;Insulin;Blood fat;Inflammatory factors;Oxidative stress index;Neurotrophic factors;mtDNA;Metabolomics;Gut microbiota;Short-chain fatty acids (SCFAs) ; | — |
Countries
China
Contacts
Public ContactZhuang Xianghua
The Second Hospital of Shandong University
Outcome results
None listed