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The effect of etomidate total intravenous anesthesia on postoperative sleep quality in elderly patients: A randomized controlled study

The effect of etomidate total intravenous anesthesia on postoperative sleep quality in elderly patients: A randomized controlled study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500099647
Enrollment
Unknown
Registered
2025-03-26
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative sleep disorder

Interventions

Etomidate group - Group Y:Anesthesia induction was carried out in sequence by intravenous administration of sufentanil at 0.3 µg/kg, etomidate at 0.2 mg/kg, and cisatracurium at 0.15 mg/kg. Anesthesia
Propofol group - Group P:Anesthesia induction was performed by intravenous administration of sufentanil at 0.3 µg/kg, propofol at 1.5 mg/kg, and cisatracurium at 0.15 mg/kg in sequence. Anesthesia mai

Sponsors

Deyang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Age>=65 years; (2) American Society of Anesthesiologists classification < = grade III; (3) Patients with elective TURP.

Exclusion criteria

Exclusion criteria: (1) ASA classification >III.; (2) Body Mass Index (BMI) 26.9; (3) Severe cardiovascular and cerebrovascular diseases are poorly controlled (history of cerebrovascular accident, myocardial infarction or unstable angina pectoris within 3 months, and preoperative blood pressure of 180/110 mm Hg or above); (4) Severe abnormal liver and kidney function; (5) Severe diabetes mellitus and related complications; (6) Long-term use of sleep-improving drugs, psychotropic drugs, and opioids; (7) Patients who have taken hormones or other immunosuppressive drugs for 10 days in the past 6 months or have a history of adrenal suppression or immune system disorders; (8) hypothyroidism; (9) Have a history of asthma; (10) Contraindications or allergies to test drugs or other anesthetic drugs.

Design outcomes

Primary

MeasureTime frame
Pittsburgh Sleep Quality Index;

Secondary

MeasureTime frame
The number of occurrences of intraoperative hypotension;Anesthesia recovery time;Recovery room stay time;Blood cortisol content;Intraoperative awareness;Nausea and vomiting;

Countries

China

Contacts

Public ContactXiong Chao

Deyang People's Hospital

15808485903@163.com+86 158 0848 5903

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026