A randomised non-inferiority trial of treatment of Mycoplasma pneumoniae pneumonia in adults with modified dose of doxycycline versus traditional dose of doxycycline in a single centre

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500099631

Enrollment

Unknown

Registered

2025-03-26

Start date

2025-04-15

Completion date

Unknown

Last updated

2025-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

adult non-hospitalized Mycoplasma pneumoniae pneumonia

Interventions

Traditional dose of doxycycline group:Traditional dose of doxycycline therapy

lower dose of doxycycline group:Modified-dose doxycycline therapy

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Patients who have not used anti-Mycoplasma pneumoniae medications within 5-10 days of onset of illness and whose PSI scores are in categories I, II, or III.

Exclusion criteria

Exclusion criteria: 1.Patients with onset of illness of more than 10 days, previous use of anti-Mycoplasma pneumoniae medications, or PSI scores in categories IV or V.

Design outcomes

Primary

Measure	Time frame
Whether lung imaging findings improved at the second week of follow-up;Time of improvement in respiratory symptoms;Post-intervention antipyretic time;	—

Countries

China

Contacts

Public ContactXing Fanfan

The University of Hongkong - Shenzhen Hospital

xingff@hku-szh.org+86 755 86913333

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026