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Exosome-based OCS scores for predicting ovarian cancer recurrence: a prospective multicenter observational cohort study

Exosome-based OCS scores for predicting ovarian cancer recurrence: a prospective multicenter observational cohort study

Status
Recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500099623
Enrollment
Unknown
Registered
2025-03-26
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian Cancer

Interventions

Control group of the training set:No recurrence after first-line treatment for ovarian cancer
Case group of the training set:Recurrence after first-line treatment for ovarian cancer
Validation set:Whether ovarian cancer recurs after first-line treatment

Sponsors

Peking Union Medical College Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Women over 18 years old; 2.Pathology confirmed stage I-IV epithelial ovarian cancer; 3.ECOG <= 2; 4.The expected survival is more than 6 months; 5.No more than 8 weeks elapsed between diagnosis and enrollment; 6.Sign informed consent;

Exclusion criteria

Exclusion criteria: 1.Ovarian tumors of non-epithelial origin; 2.A history of tumor in the past 5 years; 3.Have received systemic treatment for ovarian cancer; 4.Pregnancy; 5.Previous bilateral oophorectomy;

Design outcomes

Primary

MeasureTime frame
Evaluate the performance of the OCS recurrence prediction model and recurrence monitoring model in predicting the recurrence of ovarian cancer after first - line treatment;

Secondary

MeasureTime frame
Correlations between OCS scores and indicators such as tumor stage, best imaging efficacy assessment, chemotherapy sensitivity, and PFS;Performance of recurrence prediction models in different subgroups (different pathological subtypes of ovarian cancer, different treatment methods, etc.);

Countries

China

Contacts

Public ContactLei Li

Peking Union Medical College Hospital

lilei@pumch.cn+86 10 6915 6204

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026