Skip to content

The establishment of the normal range for the serum biomarker REG1A related to gastrointestinal mucosal injury in children and its clinical applications

The establishment of the normal range for the serum biomarker REG1A related to gastrointestinal mucosal injury in children and its clinical applications

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500099616
Enrollment
Unknown
Registered
2025-03-26
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Common organic gastrointestinal disords in children

Interventions

Gold Standard:1.The diagnosis of childhood functional gastrointestinal disorders aligns with the 2016 Rome IV diagnostic criteria for pediatric functional gastrointestinal disorders. 2.Gastrointestina
Index test:Quantitative Detection of Serum REG1A

Sponsors

Chengdu Women's and Children's Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 16 Years

Inclusion criteria

Inclusion criteria: 1.Age between 28 days and 16 years old, gender is not restricted 2.Individuals presenting with gastrointestinal symptoms and clinically diagnosed with functional or organic gastrointestinal disorders, such as acute/chronic gastritis, acute gastroenteritis, acute enteritis, inflammatory bowel disease, peptic ulcers, and functional gastrointestinal disorders 3.Parental Consent

Exclusion criteria

Exclusion criteria: 1.Combined with gastrointestinal malformations; 2.Combined with other systemic infectious or autoimmune diseases; 3.Incomplete case information, including sample collection time, subject age, and clinical background information of the sample; 4.Unqualified serum samples, including hemolysis, insufficient volume, etc.

Design outcomes

Primary

MeasureTime frame
REG1A value;Specificity;Sensitivity;

Countries

China

Contacts

Public ContactLijing Xiong

Chengdu Women's and Children's Central Hospital

xionglijing1985@uestc.edu.cn+86 186 0289 1317

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026