Stroke
Conditions
Interventions
S1+MI-BCI(stroke):MI-BCI training was performed after high-frequency rTMS treatment in S1 (30 minutes/time/day, 5 times/week for 2 weeks).
M1+MI-BCI group (Stroke):MI-BCI training was performed after high-frequency rTMS treatment in M1 (30 minutes/time/day, 5 times/week for 2 weeks).
Sham-stimulation +MI-BCI group (stroke):After sham high-frequency rTMS stimulation of M1 and S1, MI-BCI training was performed (30 minutes/time/day, 5 times/week, a total of 2 weeks).
S1+MI-BCI group (healthy subjects):MI-BCI training was performed after high-frequency rTMS treatment in S1 (30 minutes/time/day, 5 times/week for 2 weeks).
M1+MI-BCI group (healthy subjects):MI-BCI training after high frequency rTMS on M1 (30 minutes/time/day, 5 times/week for 2 weeks)
Sham-stimulation +MI-BCI group (healthy subjects):After sham high-frequency rTMS stimulation of M1 and S1, MI-BCI training was performed (30 minutes/time/day, 5 times/week, a total of 2 weeks).
Sponsors
The Seventh Affiliated Hospital of Sun Yat-sen Universit(Shenzhen)
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients with stroke 1 The diagnostic criteria of stroke formulated by the Fourth National Conference on Cerebrovascular Disease; 2 The first attack was confirmed by head CT or MRI examination, and the course of disease was more than 6 months; 3 age between 18 and 80 years old, including 18 and 80 years old, regardless of gender; 4 motor dysfunction of upper limbs and hands after stroke; 5 stable vital signs; 6 All patients signed the informed consent for treatment. Healthy subjects 1 Good physical health; 2 Age between 18 and 80 years old, including 18 years old and 80 years old, regardless of gender. 3 All subjects signed the informed consent for treatment.
Exclusion criteria
Exclusion criteria: 1 Inability to understand and cooperate with instructions due to severe cognitive impairment or mental disorder; 2 History of epilepsy; 3 other musculoskeletal or neurological disorders affecting functional recovery; 4 malignant tumors, severe heart, liver, lung, kidney dysfunction, endocrine, hematopoietic, immune system and other serious primary diseases; 5 Previous upper limb fractures, severe arthritis, and joint replacement surgery affected upper limb function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Upper Limb Motor Function Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Electroencephalogram index; | — |
Countries
China
Contacts
Public ContactQiang Lin
The Seventh Affiliated Hospital of Sun Yat-sen Universit(Shenzhen)
Outcome results
None listed