nil
Conditions
Interventions
Weaning success group:NA
weaning failure group:NA
Sponsors
AffIliated to Shanghai Jiao Tong University School of Medicine Shanghai Children's Medical Center,Hainan Branch
Eligibility
Sex/Gender
All
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: 1. High-risk premature infants who may have respiratory distress syndrome ( RDS ) ( gestational age of 28 weeks but less than 37 weeks ). 2. Premature apnea ( gestational age 28 weeks but less than 37 weeks ); 3. Severe non-uniform changes in lung diseases, such as meconium aspiration syndrome, severe pneumonia, etc. 4. Ventilation treatment for more than 48 hours, in line with the ventilator weaning criteria; 5. The family members of the children signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Respiratory distress was progressively aggravated, oxygenation could not be maintained, arterial partial pressure of carbon dioxide ( PaCO2 ) > 60 mmHg, pH < 7.25. 2. Congenital malformations : including congenital bronchial malformations, tracheoesophageal fistula, posterior nasal atresia, cleft palate, etc. 3. Cardiovascular system instability : such as hypotension, cardiac insufficiency, congenital heart disease, etc. 4. Neuromuscular disorders : such as myasthenia gravis. 5. No spontaneous breathing. In addition, emphysema, pneumothorax, pleural effusion, history of chest surgery, severe abdominal distension, local injury ( including nasal cat membrane, oral cavity, face ) are not advocated.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaphragm thickening rate ( DTF );diaphragmatic thickness at the end of respiration ( DTee );diaphragmatic thickness at the end of inspiration ( DTei );diaphragmatic activity ( DE ); | — |
Secondary
| Measure | Time frame |
|---|---|
| The ratio of diaphragmatic thickening fraction ( DTF ) to respiratory rate.; | — |
Countries
China
Contacts
Public ContactWu Saiwei
AffIliated to Shanghai Jiao Tong University School of Medicine Shanghai Children's Medical Center,Hainan Branch
Outcome results
None listed