Colorectal cancer
Conditions
Interventions
Remazolam Group:Remimazolam was used as a sedative for general anesthesia induction and intraoperative maintenance
Propofol Group:Propofol was used as a sedative for general anesthesia induction and intraoperative maintenance
Sponsors
Shaoxing people's hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Have a history of hypertension; Gender is not limited; Age 60~80 years old; ASA Class II~III.
Exclusion criteria
Exclusion criteria: Severe valvular heart disease; Coronary heart disease; abnormal liver and kidney function; Benzodiazepines contraindications; poor preoperative blood pressure control (systolic blood pressure >=180 mmHg/diastolic blood pressure >=110 mmHg); BMI >28 kg/m^2; preoperative ECG showed frequent arrhythmias.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Recovery time of consciousness;Extubation time;Dosage of vasoactive drugs during operation;Dosage of opioids during operation;Intraoperative infusion volume;Intraoperative blood pressure coefficient of variation;Plasma formic acid content; | — |
Primary
| Measure | Time frame |
|---|---|
| Time - weighted average of intraoperative hypotension; | — |
Countries
China
Contacts
Public ContactSong Qiliang
Shaoxing people's hospital
Outcome results
None listed