Pulmonary nodules
Conditions
Interventions
2.0 µ g/kg dexmedetomidine hydrochloride nasal spray:2.0 µ g/kg nasal spray dexmedetomidine was administered from 21:00 to 21:30 on the night before surgery, the first day and the second day after sur
1.0 µ g/kg dexmedetomidine hydrochloride nasal spray:1.0 µ g/kg nasal spray dexmedetomidine was administered from 21:00 to 21:30 on the night before surgery, the first day and the second day after sur
Normal saline group:1.0 µ g/kg nasal spray normal saline was administered from 21:00 to 21:30 on the night before operation, the first day and the second day after operation
Sponsors
Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1 Age range: 18-65 years old, gender not limited; 2 ASA levels I-III; 3 Electively perform VATS (wedge resection of lung lobes, segments, and lungs).
Exclusion criteria
Exclusion criteria: 1 Unilateral total lung resection; 2 Patients with sleep apnea syndrome; 3 Those who are allergic to any drugs used in this test; 4 Patients with hypotension, bradycardia and sinus arrest; 5 People with previous history of allergic rhinitis, nasal surgery and history of respiratory tract infection within the last 2 weeks; 6 Those with severe liver and kidney function abnormalities; 7 Those who have been taking sedative-hypnotic drugs for a long time (>3 months); 8 Those who are dependent on alcohol; 9 Those who are unable to communicate normally: hearing impairment, language comprehension disorder, mental illness, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of sleep disorder on the night of operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| AIS score;Objective sleep data of Fibit charge 2;PSQI score;NRS score;The incidence of delirium ;Subjective sleep rating;Postoperative recovery quality score; | — |
Countries
China
Contacts
Public ContactLinlin Zhao
Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed