Major depressive disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Meets the diagnostic criteria for depression according to DSM-5; 2.Hamilton Depression Rating Scale-17 total score >= 8; 3.Aged 6 to 18 years; 4.The patient and their guardian voluntarily participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Major medical conditions or medication use that may affect the central nervous system and immune function; 2.Substance dependence within the past 6 months or current substance abuse (excluding nicotine); 3.A history of or current comorbid psychiatric disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tryptophan metabolites (tryptophan / kynurenine / kynureic acid / quinoline acid / 3-hydroxykynurenine / serotonin); | — |
Countries
China
Contacts
Beijing HuiLongGuan Hospital