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An observational study of kynurenine metabolites in the phase-to-phase prediction of depression in children and adolescents

An observational study of kynurenine metabolites in the phase-to-phase prediction of depression in children and adolescents

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500099566
Enrollment
Unknown
Registered
2025-03-25
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major depressive disorder

Interventions

MDD:None

Sponsors

Beijing HuiLongGuan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1.Meets the diagnostic criteria for depression according to DSM-5; 2.Hamilton Depression Rating Scale-17 total score >= 8; 3.Aged 6 to 18 years; 4.The patient and their guardian voluntarily participate in the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Major medical conditions or medication use that may affect the central nervous system and immune function; 2.Substance dependence within the past 6 months or current substance abuse (excluding nicotine); 3.A history of or current comorbid psychiatric disorders.

Design outcomes

Primary

MeasureTime frame
Tryptophan metabolites (tryptophan / kynurenine / kynureic acid / quinoline acid / 3-hydroxykynurenine / serotonin);

Countries

China

Contacts

Public ContactYunYajun

Beijing HuiLongGuan Hospital

yunyj2021@163.com+86 10 83024225

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026