Skip to content

Exploration of the Mechanisms Affecting Lower Limb Motor Function Post-Stroke through fNIRS-Based HF-rTMS Combined with Mirror Therapy

Exploration of the Mechanisms Affecting Lower Limb Motor Function Post-Stroke through fNIRS-Based HF-rTMS Combined with Mirror Therapy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500099550
Enrollment
Unknown
Registered
2025-03-25
Start date
2024-09-19
Completion date
Unknown
Last updated
2025-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral hemorrhage and cerebral infarction

Interventions

Control group:General rehabilitation therapy
Intervention group 1:General rehabilitation therapy+repetitive transcranial magnetic stimulation(rTMS).
Intervention group 2:General rehabilitation therapy+repetitive transcranial magnetic stimulation(rTMS)+mirror therapy.

Sponsors

Nanchong Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.All met the diagnostic criteria of China Guidelines for the Diagnosis and Treatment of Cerebral Hemorrhage 2019 and China Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018, and confirmed stroke disease by craniocerebral CT or MRI; 2.The patient's vital signs were stable, with no serious complications of lung, liver, heart, kidney and other organs; 3.The first onset, and one side of the limb paralysis, the course of the disease is more than two weeks; 4.Patients with good cognitive function [simple cognitive status checklist (MMSE)> 23 points], good mental condition, can cooperate with evaluation and treatment; 5.The patient and their family members were informed about this study, agreed to participate in this study, and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Wearing pacemakers, metal implants and other metal implants in the skull, or patients with skull defects, epilepsy, pregnancy, lactation, or women of childbearing age who have not taken reliable contraceptive measures; 2.Severe systemic diseases cannot participate in the study: patients with severe respiratory, cardiac, liver, kidney, endocrine and hematopoietic diseases, such as congestive heart failure, arrhythmia, hypertension without control; 3.The limbs have obvious deformity or other diseases affecting the movement of the lower limbs, such as: serious infection of the lower limbs, contracture, joint surgery, amputation, fracture, rheumatism or rheumatoid arthritis; 4.Severe speech, vision, hearing and other disorders (such as deaf people) or mental disorders affecting the examination and treatment; 5.Uncontrolled seizures or epilepsy; 6.Severe cognitive dysfunction; 7.Patients who have recently participated in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer lower extremity function;

Secondary

MeasureTime frame
Ability to perform activities of daily living;

Countries

China

Contacts

Public ContactLi Huifeng

Nanchong Central Hospital

940986941@qq.com+86 182 8414 0113

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026