Painless abortion
Conditions
Interventions
Group A:0.1mg/kg of esketamine was administered 3 minutes before the operation, and propofol medium and long chain injection (Sichuan National Rui) was administered 3 minutes later. The operation bega
Group B:0.2mg/kg of esketamine was administered 3 minutes before the operation, and propofol medium and long chain injection (Sichuan National Rui) was administered 3 minutes later. The operation bega
Group C:0.3mg/kg of esketamine was administered 3 minutes before the operation, and propofol medium and long chain injection (Sichuan National Rui) was administered 3 minutes later. The operation bega
Sponsors
Jintang County first People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1, Age 18-40 years old, BMI(18.5-30kg/m2); 2, Routine examination is basically normal (liver and kidney function, coagulation function, blood routine, electrocardiogram, chest CT); 3, No mental disorders, mental disorders and other diseases; 4, ASA classification: I-II level; Cardiac function: Grade 1-2.
Exclusion criteria
Exclusion criteria: 1. Mental patients; 2, Esketamine drug history and allergy, or use sedative drugs and drug dependence; 3, Infectious diseases and blood system diseases; 4. Patients who are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Before anesthesia (T0), at curettage (T1), and at the end of surgery (T2);Heart rate;Pulse oxygen saturation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Propofol dosage;Time for eyelash reflexes to disappear;Recovery time (time from withdrawal to eye opening);Time for patient to get out of bed (PACU observation);Add the number of propofol;The number of adverse reactions;VAS pain score; | — |
Countries
China
Contacts
Public ContactLi Deyuan
First People's Hospital of Jintang County, Sichuan Province
Outcome results
None listed