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Efficacy evaluation and influencing factors analysis of photodynamic therapy in the treatment of oral leukoplakia

Efficacy evaluation and influencing factors analysis of photodynamic therapy in the treatment of oral leukoplakia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500099540
Enrollment
Unknown
Registered
2025-03-25
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral leukoplakia, OLK

Interventions

Group of oral oral leukoplakia patients with photodynamic therapy:None

Sponsors

Hospital of Stomatology, SunYat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: a) Patients diagnosed with oral leukoplakia by clinical and pathological conditions. The diagnostic criteria refer to the definition and grading standards of oral leukoplakia by the Professional Committee of Oral Mucosal Diseases of the Chinese Stomatological Association. If there is no progress in the condition within the past 2 years, the histopathological examination results within the past 2 years will be recognized; b) Completed at least one course of PDT treatment.

Exclusion criteria

Exclusion criteria: a) Patients with a history of malignant tumors in the oral cavity or other body parts; b) Patients with incomplete clinical pathological information or follow-up records.

Design outcomes

Primary

MeasureTime frame
Percentage Reduction in Area,%RA;

Secondary

MeasureTime frame
Total response rate, TR%;Initial treatment response rate, ITR%;Complete response rate, CR%;Complete and significant response rate, CR&SR%;recurrence rate;malignant transformation rate, MTR;

Countries

China

Contacts

Public ContactTao Xiaoan

Hospital of Stomatology, SunYat-sen University

taoxiaoa@mail.sysu.edu.cn+86 135 3896 5917

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 13, 2026