Liver-related diseases
Conditions
Interventions
Sandwich TAP group:Bilateral subcostal transversal plane block and lateral cutaneous branch block of subcostal intercostal nerve
Traditional TAP:Classic subcostal bilateral ventral transverse plane block
Sponsors
Shanghai Sixth People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with liver-related disease and proposed to undergo "open liver surgery"; 2.ASA Level I-II; 3.Age 18-65 years old.
Exclusion criteria
Exclusion criteria: 1.History of liver surgery; 2.Allergies or contraindications to the drugs used in the trial; 3.Abnormal coagulation function; 4.Long-term use of opioids; 5.Patients with severe heart, liver, kidney function abnormalities and mental abnormalities; 6.Puncture site infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of postoperative recovery (QoR-40 Scale);Proportion of patients with moderate to severe pain 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS scores at 2, 6, 12, 24 hours and one week after surgery;Plasma levels of VEGF-C, IL-6, glucocorticoid and adrenaline before, immediately after and 24h after surgery;The cumulative amount of opioids used in the 24 hours after surgery;Occurrence of opioid-related side effect; | — |
Countries
China
Contacts
Public ContactKong Sai
Shanghai Sixth People’s Hospital
Outcome results
None listed