Infertility
Conditions
Interventions
Experimental group (AF group):Intravenous alfentanil hydrochloride 8µg/kg
Control group (Group F):Intravenous fentanyl 1.2µg/kg
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. ASA grade I.~II., BMI of 18~28 kg/m, operation time <= 15 minutes. 2. Be aware and be able to communicate with doctors. Able to understand the visual analogue scale under the guidance of a physician(Visual Analogue Scale,VAS); 3. Patients with normal preoperative routine ECG and liver and kidney function; 4. No history of cardiovascular diseases such as hypertension and coronary heart disease in the past; 5. No serious hematologic diseases; 6. No recent upper respiratory tract infection.
Exclusion criteria
Exclusion criteria: 1. Long-term history of use of narcotic analgesics, sedatives or non-steroidal anti-inflammatory drugs; 2. History of neurological and psychiatric diseases before surgery; 3. Patients with a history of habitual reflux vomiting.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Apnea;Diaphragmatic excursion; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body mass index;Age;American Society of Anesthesiologists Physical Status Classification;Number of egg retrieval cycles;The number of follicles >= 14 mm was monitored;Propofol induction dose;Number of propofol additions;Total propofol dosage;Propofol effector chamber concentration;Duration of surgery;Wake up time;Heart rate;Mean arterial pressure;Respiratory rate;Oxygen saturation;End-tidal carbon dioxide;Perioperative adverse events (hypoxemia, respiratory depression, hypotension, bradycardia, nausea and vomiting, vertigo, blurred vision);Modified Observer"s Assessment of Alertness/Sedation;Visual Analogue Scale;Number of eggs retrieved;Patient comfort score;Surgeon satisfaction score; | — |
Countries
China
Contacts
Public ContactGuangying Zhang
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed