Ceft lip and palate
Conditions
Interventions
Midazolam low dose group:Midazolam was taken orally 0.3mg/kg before surgery
Midazolam high dose group:Midazolam was taken orally 0.5mg/kg before surgery
Normal saline group:Oral equivalent dose of saline before surgery
Sponsors
Stomatological Hospital Affiliated to Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
No minimum to 14 Years
Inclusion criteria
Inclusion criteria: 1. Receiving cleft lip and palate surgery; 2. Aged 0-14 years old; Body weight <=40kg; 3. Signed informed consent; 4. Normal liver and kidney function; 5. ASA grade 1 or 2.
Exclusion criteria
Exclusion criteria: 1. Patients and their families refuse to participate; 2. People with severe allergies; 3. Liver and kidney dysfunction; 4. Have a serious systemic disease, such as heart failure; 5. Have uncorrected malignant arrhythmias; 6. Abnormal somatosensory function; 7. There are central or peripheral nervous system lesions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation score after 30 minutes of administration;Mask acceptance score at induction;Postoperative agitation score;Postoperative pain score;Extubation time;Awakening time;Resuscitation room stay time;Pre-sedation vital signs (blood pressure, respiration rate, heart rate, oxygen saturation);Vital signs after sedation (blood pressure, respiration rate, heart rate, oxygen saturation);Vital signs after intubation (blood pressure, respiration rate, heart rate, oxygen saturation);Vital signs after extubation (blood pressure, respiration rate, heart rate, oxygen saturation);Vital signs upon awakening (blood pressure, respiration, heart rate, oxygen saturation); | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative respiratory depression;Postoperative nausea and vomiting;Postoperative bed fall; | — |
Countries
China
Contacts
Public ContactXiaoping Zhang
Stomatological Hospital Affiliated to Wenzhou Medical University
Outcome results
None listed