Overweight and obesity
Conditions
Interventions
The lifestyle intervention plus meal replacement (MR)-assisted intermittent fasting group:Participants in the MR group received a dietary intervention that included a 5:2 intermittent fasting regimen.
The lifestyle intervention alone:All participants were instructed to adhere to prescribed diets. Participants in LIA group consumed a calorie-restricted diet (1200-1400 kcal/d for men and 1000-1200 kc
Sponsors
Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: We recruited participants aged 18-60 years with a stable weight change (± 4 kg) over the last three months, and met at least one of the following criteria: overweight with BMI >= 24 kg/m2, or fat mass percentage >=30% for women and >=25% for men, or waist circumference >=85 cm for women and >=90 cm for men.
Exclusion criteria
Exclusion criteria: 1. Cancer, liver and kidney dysfunction, acute cardiovascular and cerebrovascular disease, acute infectious disease, psychosis, bulimia nervoides, anorexia, gastrointestinal disease, or history of surgery within the past three months; 2. Pregnancy, lactation, oral contraceptives or hormone replacement therapy; 3. Endocrine or monogenic secondary obesity; 4. Artificial pacemakers. Participants who had started dieting to lose weight were excluded. Also excluded were participants who had taken glucose-lowering medications, psychotropic medications, weight-loss medications, or other medications known to affect body weight or energy metabolism during the 14 days before the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body weight; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body composition;Biochemical assays; | — |
Countries
China
Contacts
Public ContactChen Yahong
Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University
Outcome results
None listed