Coronary heart disease
Conditions
Interventions
Traditional ventilation mode group(PV):PEEP = 5 cmH2O
Driving pressure guided ventilation group (DP group):PEEP is set to the peep value corresponding to the minimum driving pressure
Sponsors
Tianjin First Central Hospital
Eligibility
Sex/Gender
All
Age
45 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age 45-70 years old; 2. ASA grade II~III; 3. Normal preoperative pulmonary function test; 4. Undergo cardiopulmonary bypass grafting for the first time.
Exclusion criteria
Exclusion criteria: 1. Preoperative patients with asthma and chronic obstructive pulmonary disease; 2. Suffering from tuberculosis and lung infection; 3. Heart failure, left ventricular ejection fraction less than 40%; 4. Patients with other serious diseases, accompanied by contraindications to surgery, and not suitable for surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxygenation index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory parameters;Driving pressure;Lung compliance;Pulmonary complications 7 days after surgery;Postoperative extubation time;ICU staying time; | — |
Countries
China
Contacts
Public ContactLi Hongxia
Department of Anesthesiology, Tianjin First Central Hospital
Outcome results
None listed