Multilocular Separated Pleural Effusion
Conditions
Interventions
"Center solubilization" group:None
"Multi-point solution" group:None
"Conventional single point method" group:None
Sponsors
The First Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Poor drainage of pleural effusion, clinical requirement for urokinase therapy, and ultrasound shows multilocular septic pleural effusion; 2.Without severe coagulation dysfunction: TT and APTT should be less than 2 times of the normal range; 3. Without recent history of anticoagulant treatment; 4. The patient voluntarily participates in the treatment and signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Severe heart, lung, liver, kidney and other systemic diseases and bronchopleural fistula; 2. History of thrombolytic therapy is prohibited in patients with certain bleeding disorders, such as hemorrhagic stroke; 3. History of allergy to urokinase, sonovite, and shezoan contrast agents; 4. Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effective rate of urokinase treatment ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total dose of urokinase;Total retention time of urokinase; | — |
Countries
China
Contacts
Public ContactQing Tang
The First Affiliated Hospital of Guangzhou Medical University/National Centre for Respiratory Medicine
Outcome results
None listed