Alzheimers disease
Conditions
Interventions
paying attention to mood and how to adjust emotions
and how to control basic diseases such as hypertension, diabetes and hyperlipidemia
Virtual reality intervention group:Use headset HTC Vive Pro, equipped with controller, static seat, use game scenes, such as cutting fruit cutting, whack-a-mole and other rich scenes for training. At
controlling risk factors of cognitive decline such as reducing sedentary, increasing exercise and interpersonal communication
paying attention to monitoring and adjusting sleep
Standard CARE group:Standard care, using standard care for Alzheimers disease (AD), covering medication, cognitive function training, physical exercise, psychological support and other contents. The c
Sponsors
The First Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
55 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Age: 55-90 years old; 2. Primary school education or above, visual and hearing barrier-free, can cooperate to complete the evaluation; 3. Overall cognitive function assessment: AD: MMSE: 15 points and 23 points, clinical AD rating scale (CDR)=0.5-1 score; 4. To participate in the study, obtained the consent of the guardian and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1.Have a history of neuropsychiatric diseases, such as cerebrovascular disease, depression, schizophrenia, drug dependence, intracranial tumor, refractory epilepsy, Parkinson's disease, normal pressure hydrocephalus, brain tumor and head trauma surgery, etc.; 2.Heart, liver, kidney, hematopoietic system and endocrine system diseases that seriously affect cognitive function; 3. The head magnetic resonance or CT has infarct lesions, microbleeding and space occupation lesions; 4. Are receiving other non-pharmacological interventions; Patients who met the above criteria were advised by the attending physician and recruited to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall cognitive function assessment;Multidimensional cognitive function assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Imaging acquisition data;electroencephalogram data;Functional near-infrared spectroscopy (fNIRS); | — |
Countries
China
Contacts
Public ContactYi Zhu
The First Affiliated Hospital of Nanjing Medical University
Outcome results
None listed