Skin aging
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Age range from 30 to 65 years old, regardless of gender (2) Healthy body, without serious cardiovascular, digestive, endocrine, immune, nervous system and other major diseases history; No history of mental or psychological abnormalities (3) Meets the indications for 1064nm nanosecond laser rejuvenation treatment of the back of the hand, such as hand pigmentation, rough skin, sagging, and poor elasticity (4) The subjects fully understand the experimental content, voluntarily participate in the experiment, and have signed an informed consent form (5) No history of skin diseases such as drug allergies, skin tumors, dermatitis, eczema, etc (6) Able to receive treatment, collect data according to research requirements, and cooperate with visits
Exclusion criteria
Exclusion criteria: (1) Within 6 months, the hand has received treatment with botulinum toxin, hyaluronic acid, collagen, autologous fat, etc (2) Within 6 months, the hand has received phototherapy or chemical exfoliation treatment (3) Active inflammation or ulceration of the hand skin (4) Pregnant, pregnant, and lactating women (5) Those who use Chinese herbal medicine, sedatives, or other addictive drugs (6) Alcoholics, mental illness patients, or those who cannot cooperate with treatment and research according to medical advice (7) Patients with a history of photosensitive diseases (chronic actinic dermatitis, systemic lupus erythematosus, etc.), skin photosensitivity, porphyrin allergy, porphyria, etc (8) Individuals who take or apply photosensitive drugs or hormones internally or externally
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin slasticity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin thickness;Skin texture;Skin pigment;Adverse reaction rate; | — |
Countries
China
Contacts
Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine