postoperative delirium
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. patients undergoing elective noncardiac surgery under general anesthesia; 2. age >=65 years; 3. ASA classification I-IV; 4. good preoperative cognitive status and no verbal communication deficits; 5. educational level to complete preoperative cognitive function tests.
Exclusion criteria
Exclusion criteria: 1. emergency surgery or major surgery such as cardiovascular surgery within one month; 2. preoperative Mental Status Examination (MMSE) score <23; 3. other major neurological disorders such as central nervous system infection, head trauma, epilepsy, multiple sclerosis, etc.; 4. uncontrolled cardiovascular and cerebral vascular diseases, severe liver and renal failure, and hemorrhagic disorders; 5. failure of vital organs, mental or consciousness disorders; 6. drug abuse, and long-term use of steroids and hormonal drugs. Disorders; 6. Drug addiction, abuse of psychotropic substances, and long-term use of steroids and hormonal drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative POD within 1-7 days; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospital stay;Postoperative three-year mortality rate; | — |
Countries
China
Contacts
Qingdao Municipal Hospital