Relationship between preoperative 25(OH)D3 level and postoperative delirium in elderly patients undergoing hip and knee arthroplasty and its predictive value

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500099471

Enrollment

Unknown

Registered

2025-03-24

Start date

2024-04-01

Completion date

Unknown

Last updated

2025-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Delirium

Interventions

Preoperative 25(OH) D3-deficient group:None

Preoperative 25(OH)D3 Normal Group:None

Eligibility

Sex/Gender

All

Age

60 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. ASA grade I-III; 2. Patients and their families are informed about the study; 3. Age 60-90 years; 4. Patients who will undergoning hip or knee replacement and meet surgical requirements; 5. Complete clinical data.

Exclusion criteria

Exclusion criteria: 1. Severe visual and hearing impairment; 2. Previous psychiatric history; 3. Recent use of psychotropic drugs such as sedatives; 4. Patients with cognitive dysfunction, mental illness or dementia before operation; 5. Vital organ function impairment; 6. Have taken vitamin D preparations or other drugs that can affect vitamin D metabolism within six months.

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative delirium;	—

Secondary

Measure	Time frame
Incidence of long-term cognitive impairment;	—

Countries

China

Contacts

Public ContactTong Xingyu

Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University

2433928723@qq.com+86 180 1627 7207

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026