Infantile infectious diarrhea
Conditions
Interventions
Control,C:None
Infantile diarrhea,ID:None
IDMPR:Receive conventional treatment with montmorillonite powder, along with oral probiotics
IDMPL:He received conventional treatment with montmorillonite powder and an oral placebo
Sponsors
The Second People's Hospital of Jingdezhen
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The clinical manifestations were abdominal distension, diarrhea, abdominal pain, increased frequency of stool, watery stool, loss of appetite, etc. 2. The onset time was more than 5 days, and there was no digestive ulcer or digestive system tumor after relevant examination. 3. No other drugs or probiotics were used in the first 3 months after the completion of treatment, and parents agreed to sign informed consent.
Exclusion criteria
Exclusion criteria: 1. High fever persists, there is secondary diarrhea. 2. Have a recent history of antibiotic or antidiarrheal therapy, have a serious active viral or bacterial infection, and have not been controlled by treatment. 3.Have any other serious or chronic illness that the investigator believes may affect the patient's treatment, follow-up, or evaluation. It includes any uncontrolled and clinically significant neurological, psychiatric, immune-regulatory, metabolic and infectious diseases. 4. Patients who are not suitable for probiotic-assisted therapy after diagnosis and evaluation by clinicians.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut microbiota composition;Observation on the efficacy of diarrhea;Hart diarrhea scale;High-throughput sequencing of stool samples;Detection of the source of infection; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical blood test; | — |
Countries
China
Contacts
Public ContactHongying Yu
Jingdezhen Second People's Hospital
Outcome results
None listed