Idiopathic scoliosis
Conditions
Interventions
Experimental Group:rTMS true stimulation and conventional psychological counseling.
Control Group:rTMS sham stimulation combined with conventional psychological counseling.
Sponsors
The Third Affiliated Hospital Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
10 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1.The patient was diagnosed with adolescent idiopathic scoliosis; 2.Age 10-18 years old; 3.Risser index 0-2; 4.Cobb Angle 20-40; 5.orthosis treatment, wearing orthosis for more than 3 months, wearing time more than 12 hours per day, and never undergoing surgical treatment; 6.Depressive disorder meets the diagnostic criteria of ICD-10; 7.Patients with mild to moderate depression (HAMD scale (24 items) scores of 8-35); 8.Stable vital signs and able to complete the study protocol; 9.Had never taken antidepressant drugs; 10.Informed consent was signed by the participants and their guardians;
Exclusion criteria
Exclusion criteria: 1.Any lifelong mental disorder, intellectual disability, substance dependence or abuse (other than nicotine and caffeine, bipolar disorder, obsessive-compulsive disorder, post-traumatic stress disorder or eating disorder) within the past year; 2.Metal or electronic implants (e.g., pacemakers, cochlear implants, deep brain stimulators, aneurysm clips, ventriculoperitoneal shunt internal fixation devices, etc.); 3.Any history of neurological disease or epilepsy; 4.Unstable physical condition; 5.Contraindications of rTMS and fNIRS, including large skull defect, restlessness, alcohol abuse, etc; 6.Other serious diseases that may affect the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hamilton depression scale,HAMD-24 score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Scoliosis Research Society-22,SRS-22 score;Brace Questionnaire,BrQ score;Cobb angle;Brace wearing time;Verbal fluency task ,VFT; | — |
Countries
China
Contacts
Public ContactHe Lei
The Third Affiliated Hospital Sun Yat-sen University
Outcome results
None listed