Acute respiratory distress syndrome
Conditions
Interventions
Control Group:Morphine was given 1.0~2.5mg/h to maintain a CPOT score of <3
Observation group:Ocelidine 2-20 µg/kg/h was given and the CPOT score was maintained <3 points
Sponsors
Shandong Rehabilitation Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age >=18 years and 72h; 4.No allergic reaction to the drugs used in this study; 5.The informed consent form shall be signed by the patient and his family.
Exclusion criteria
Exclusion criteria: 1.Expected survival time < 14 days; 2.Pregnancy or lactation; 3.Patients with myasthenia gravis, acute myocardial ischemia, or severe arrhythmias; 4.Severe head injury, brain tumor, coma, status epilepticus, etc; 5.Patients with a history of alcohol or drug abuse or chronic pain requiring long-term use of analgesic and sedative drugs; 6.Any condition that impedes the proper assessment of cognitive function, such as language and sensory disorders or mental disorders (language difficulties or sexual dysfunction); 7.Participate in other exploratory clinical trials within 3 months before screening; 8.With malignant lesions; 9.Liver, kidney and other organ function failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analgesic effect; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical indicators;Hemodynamics;Adverse reactions; | — |
Countries
China
Contacts
Public ContactDai Jingcun
Shandong Rehabilitation Hospital
Outcome results
None listed