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The role of free testosterone in the progression of newly diagnosed advanced metastatic prostate cancer

The role of free testosterone in the progression of newly diagnosed advanced metastatic prostate cancer: a prospective, single-center study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500099387
Enrollment
Unknown
Registered
2025-03-24
Start date
2025-03-29
Completion date
Unknown
Last updated
2025-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metastatic prostate cancer

Interventions

Observations group:none

Sponsors

The Second Hospital of Tianjin Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
40 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1.The patient underwent prostate biopsy and was pathologically diagnosed as adenocarcinoma (including acinar adenocarcinoma, ductal adenocarcinoma, and intraductal carcinoma); 2.The clinical stages were M1 (CT, ECT, PET-CT); 3. Patients receiving ADT after diagnosis; 4. Patients with regular follow-up and timely detection of testosterone, free testosterone and PSA according to the study protocol; 5. The patient had no history of other malignant tumors of urinary system; 6. Patient's medical records and follow-up data were complete.

Exclusion criteria

Exclusion criteria: 1.Prostate cancer patients with other primary tumors; 2. The pathological diagnosis was urothelial origin, intraductal carcinoma, sarcoma, and prostate neuroendocrine carcinoma; 3. Patients taking other anti-tumor drugs during ADT treatment; 4. Patients receiving radiotherapy and/or chemotherapy during ADT treatment; 5. The patient is diagnosed with a neuropsychiatric disease or the use of drugs that may affect the central nervous system during treatment; 6. The patient is diagnosed with hepatitis B, AIDS, tuberculosis and other infectious diseases; 7. Patients with stroke, coronary heart disease, chronic renal insufficiency, chronic liver insufficiency and other major diseases; 8. The patient is complicated with systemic metabolic diseases such as thyroid, adrenal, blood system and pituitary gland

Design outcomes

Primary

MeasureTime frame
free testosterone;

Secondary

MeasureTime frame
Prostate-specific antigen;

Countries

China

Contacts

Public ContactWen Simeng

The Second Hospital of Tianjin Medical University

Simeng_wen@tmu.edu.cn+86 136 8210 4008

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026