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Effect of lactate/albumin ratio on 28-day mortality in patients with sepsis:a multicenter prospective cohort study

Effect of lactate/albumin ratio on 28-day mortality in patients with sepsis: a multicenter prospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500099373
Enrollment
Unknown
Registered
2025-03-21
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

Sponsors

The First Affiliated Hospital of Guangxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Meeting the Sepsis 3.0 diagnosis criteria: According to the diagnostic criteria in "The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3.0)" released by the European Society of Intensive Care Medicine in 2016, the patient has a confirmed or suspected infection, and the Sequential Organ Failure Assessment (SOFA) score is >= 2 points; (2) Age >= 18 years old; (3) First-time admission to the ICU. For patients with multiple ICU admissions, only the data from their first ICU admission will be included; (4) The patient or their legal representative has signed an informed consent form, agreeing to participate in this study and cooperate with the follow-up.

Exclusion criteria

Exclusion criteria: (1) The length of stay in the ICU is less than 1 day; (2) Pregnant women and lactating women; (3) Patients with advanced malignant tumors or end-stage chronic diseases (such as the uremic stage of chronic renal failure, the decompensated stage of advanced liver cirrhosis, etc.) with an expected survival period of less than 28 days; (4) Patients who have received long-term immunosuppressive therapy before admission (such as long-term use of immunosuppressants after organ transplantation, long-term use of high-dose glucocorticoids or immunomodulators for autoimmune diseases like systemic lupus erythematosus, etc.), which may affect the accuracy of the research results; (5) Patients who are unwilling to participate in the study.

Design outcomes

Primary

MeasureTime frame
lactate/albumin ratio;

Secondary

MeasureTime frame
Serum Lactate;Serum Albumin;

Countries

China

Contacts

Public ContactHuang Debin

The First Affiliated Hospital of Guangxi Medical University

hdeb@sina.com+86 138 7814 8875

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026