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When combining different doses of sufentanil, 90% of the effective dose of cyclopofol inhibits laryngeal mask placement in children

When combining different doses of sufentanil, 90% of the effective dose of cyclopofol inhibits laryngeal mask placement in children

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500099371
Enrollment
Unknown
Registered
2025-03-21
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Group C1 :0.1 µg/kg sufentanil+cyclosporine
Group C2:0.15 µg/kg sufentanil+cyclosporine
Group C3:0.2 µg/kg sufentanil+cyclosporine

Sponsors

Third Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 6 Years

Inclusion criteria

Inclusion criteria: 1. Children undergoing elective general anesthesia surgery; 2.. ASA Class I or II; 3. Age 3~6 years old; 4. Gender is not limited; 5. Body mass index 13~20kg/m^2.

Exclusion criteria

Exclusion criteria: 1. Predictable difficulty in the airway; 2. Patients with upper respiratory tract infection in the past 2 weeks; 3. Anemia, malnutrition, abnormal liver and kidney function; 4. Severe cardiovascular disease; 5. Persons with intellectual disabilities; 6. Have neuropsychiatric diseases; 7. History of taking sedative-hypnotic drugs.

Design outcomes

Primary

MeasureTime frame
ED90 of ciprofol required for smooth LMA insertion ;

Secondary

MeasureTime frame
The time to loss of consciousness;Incidence of adverse reactions;

Countries

China

Contacts

Public ContactJi Leting

Third Affiliated Hospital of Zhengzhou University

jlt0001@126.com+86 185 3800 6729

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026