Acute Leukemia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meeting the diagnostic criteria for acute myeloid leukemia (AML); 2. Age from18 to 60 years old; 3. Absence of hepatic, renal, and digestive system diseases, other tumor diagnoses, immunodeficiency, and infectious diseases; 4. No use of antibiotics or immunoecological modulators within 30 days prior to hospitalization; 5. Barthel Index score for activity ability >=60 points, with body mass index (BMI) ranging from 18.5 kg/m² to 28 kg/m²; 6. Central venous catheter administration of chemotherapeutic agents.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. Pre-existing infection (bacterial, fungal, or viral) or fever prior to hospitalization; 3. Primary gastrointestinal diseases including but not limited to Crohn's disease, ulcerative colitis, celiac disease, and short bowel syndrome; 4. Any documented gastrointestinal disorders associated with strictures, malignancies, and regional ischemia; 5. Psychiatric conditions or disorders that may interfere with study procedures or outcomes; 6. Incomplete medical records.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CD4+T lymphocyte;CD8+T lymphocyte;MBI-LCBIs; | — |
Secondary
| Measure | Time frame |
|---|---|
| Diamine Oxidase;Bacterial endotoxin;Costs Related to Bloodstream Infection Treatment;White blood cell;Hemoglobin;Platelet";High-sensitivity C-reactive protein;Blood culture;Body temperature; | — |
Countries
China
Contacts
The First Affiliated Hospital of Guangxi Medical University