pain
Conditions
Interventions
test group:The test group was configured with oxelidine 20mg and normal saline into 200ml, and was divided into two load doses of oxelidine, 0.75 mg each time, with an interval of 10 min. The total am
control group:The control group was configured with sufentanil 3ug/kg(not more than 100ug) and normal saline were configured into 200ml, the load was 3ml, the PCA dose was 3mL, and the locking time wa
Sponsors
Hefei Second People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.For patients with laparoscopic total hysterectomy, ASA anesthesia grade I ~ III; 2.Patients aged 18 years<= age <=65 years, BMI:18-28kg/m²; 3.All patients voluntarily participated in this study and signed informed consent before surgery.
Exclusion criteria
Exclusion criteria: 1. Patients allergic to oxelidine and other narcotic drugs; 2. History of postoperative severe nausea and vomiting; 3.Patients with impaired language, intelligence, understanding, and inability to communicate normally; 4.Patients with a history of neuropsychiatric disorders, drug dependence and alcoholism; 5.Patients with serious cardiovascular and cerebrovascular diseases or major organ dysfunction before surgery; 6. Intraoperative conversion to laparotomy. ?7.Patients with abnormal electrocardiogram, such as QT interval > 450ms.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| painseverity;Patient controlled analgesia press times;The dosage of remedial analgesics used; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recovery situation;Adverse reactions (nausea, vomiting, dizziness, respiratory depression) occurred ; | — |
Countries
China
Contacts
Public ContactBianbian Wang
The Second People's Hospital of hefei
Outcome results
None listed