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Clinical study of ciprofol inhibiting the reaction of tracheal intubation under general anesthesia in patients with preoperative anxiety

Clinical study of ciprofol inhibiting the reaction of tracheal intubation under general anesthesia in patients with preoperative anxiety

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500099336
Enrollment
Unknown
Registered
2025-03-21
Start date
2025-03-26
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preoperative anxiety

Interventions

Anxiety group (group A):Sequential experiment: The initial dose of ciprofol was 0.4 mig/kg. The dose-rise and fall ratio of the adjacent interval was 1:1.1. If the positive reaction was positive, the
Non-anxiety group (group C):Sequential experiment: The initial dose of ciprofol was 0.4 mg/kg. The dose-rise and fall ratio of the adjacent interval was 1:1.1. If the positive reaction was positive, t

Sponsors

People’s Hospital of Qiannan
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with elective endotracheal intubation under general anesthesia were selected, gender was not limited, age >=18 years, BMI = 18.5~28 kg/m^2, ASA grade I or II.

Exclusion criteria

Exclusion criteria: He has a history of allergy to propofol, eggs and soy products, a history of psychiatric illness, a history of hypertension, arrhythmia, and drugs that affect HR and BP, and is assessed as a difficult airway before surgery.

Design outcomes

Primary

MeasureTime frame
Tracheal intubation reaction;HR;MAP;Oxygen saturation;

Secondary

MeasureTime frame
Adverse reaction;Age;BMI;ASA grading;

Countries

China

Contacts

Public ContactChen Lvlv

People’s Hospital of Qiannan

CHENLULUzan@163.com+86 182 7088 4093

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026