postoperative pain
Conditions
Interventions
liposomal bupivacaine group:Nerve block was performed using 30 ml of 0.665% liposomal bupivacaine: 20 ml for sciatic nerve block at the popliteal fossa and 10 ml for saphenous nerve block in the adduc
Ropivacaine group:Nerve block was carried out using 30 ml of 0.375% ropivacaine: 20 ml for sciatic nerve block at the popliteal fossa and 10 ml for saphenous nerve block in the adductor canal.
Sponsors
Gansu Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Patients who meet the diagnostic criteria and have a fracture type of bimalleolar or trimalleolar fracture; (2) Patients aged between 18 and 75 years old, with ASA grade I- II; (3) Patients who voluntarily accept nerve block treatment and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Pregnant or lactating patients; (2) Patients complicated with peripheral nerve injury or lesion; (3) Patients with a previous history of specific allergic diseases (such as asthma, urticaria, eczema, etc.) or known allergies to anesthetic drugs; (4) Patients suffering from mental disorders, epilepsy, or having intellectual abnormalities; (5) Patients with inflammation, ulcers, scars, or damage around the skin at the site where nerve block is to be administered; (6) Patients with a history of long-term use of analgesic drugs or a history of alcohol abuse; (7) Patients with a previous history of chronic neuropathic pain.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| The time of the first administration of analgesic drugs within 72 hours and the total consumption of analgesic drugs;Quality of Postoperative Recovery Score;The incidence rate of nausea and vomiting after the operation; | — |
Countries
China
Contacts
Public ContactXue Jianjun
Gansu Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed