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A multicenter, randomized, controlled study on the success rate of biliary intubation in patients with common bile duct stones using endoscopic retrograde direct cholangioscopy (ERDC) and endoscopic retrograde cholangiopancreatography (ERCP)

A multicenter, randomized, controlled study on the success rate of biliary intubation in patients with common bile duct stones using endoscopic retrograde direct cholangioscopy (ERDC) and endoscopic retrograde cholangiopancreatography (ERCP)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500099332
Enrollment
Unknown
Registered
2025-03-21
Start date
2025-03-31
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Choledocholithiasis

Interventions

Traditional ERCP group:Traditional ERCP technique is used for biliary catheterization, and nipple incision and dilation are completed under X-ray fluoroscopy for stone removal (if stone removal is not
ERDC group:Using ERDC technology for biliary intubation, after successful completion of nipple incision and dilation under X-ray fluoroscopy, and stone removal (if stone removal is not possible, a bil

Sponsors

Sichuan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Imaging confirms the presence of common bile duct stones; 2. There is laboratory evidence of biliary obstruction (such as ALP and GGT increasing by more than 2 times compared to normal values); 3. Age range: 18-80 years old.

Exclusion criteria

Exclusion criteria: 1. Pregnant women, allergies to contrast agents, heart and lung dysfunction, severe liver and kidney dysfunction, and severe coagulation dysfunction; 2. Unable to cooperate with ERCP patients; 3. Patients with upper gastrointestinal stenosis or obstruction, where endoscopy cannot reach the descending segment of the duodenum; 4. Individuals with a history of subtotal gastrectomy leading to changes in the anatomical structure of the digestive tract; 5. Patients with acute pancreatitis or acute exacerbation of chronic pancreatitis; 6. Individuals who have previously undergone treatment with duodenal papilla sphincterotomy; 7. Patients with duodenal papillae fistula caused by natural stone expulsion or previous surgical cholangioscopy exploration.

Design outcomes

Primary

MeasureTime frame
ERCP intubation success rate;

Secondary

MeasureTime frame
Incidence of complications;Difficulty intubation rate;

Countries

China

Contacts

Public ContactXiaogang Liu

Sichuan Provincial People's Hospital

xgliu2003@aliyun.com+86 189 8183 8269

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026