Parkinson's Disease
Conditions
Interventions
Experimental group:None
Control group:None
Sponsors
Tongji Hospital of Tongji University
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 50-80 years old, male or female; 2. Able to walk independently for at least 25 minutes without the need for assistive devices; 3. If the diagnosis of primary Parkinson's disease is made, and the Hoehnand Yahr stage is in stage I-III, the PD patient group is included.
Exclusion criteria
Exclusion criteria: 1. Diseases combined with other neurological pathologies (such as various types of dizziness, cerebrovascular diseases, traumatic brain injuries); 2. Major depressive disorder, bipolar or schizophrenia according to ICD 11 criteria; 3. Musculoskeletal diseases, visual impairment or eye diseases that affect smooth walking; 4. Clinically diagnosed with dementia or severe cognitive impairment (MMSE< 24 points); 5. History of previous treatments that may alter brain function (such as TMS, DBS, etc.); 6. Patients with severe PD tremor, essential tremor and other diseases that affect gait.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relative Concentration of Oxygenated Hemoglobin in the Cerebral Cortex(HbO2);surface electromyography (sEMG); | — |
Secondary
| Measure | Time frame |
|---|---|
| Unified Parkinson's Disease Rating Scale;Mini-Mental State Examination; | — |
Countries
China
Contacts
Public ContactYuhui Chen
Tongji Hospital of Tongji University
Outcome results
None listed