Postoperative pain
Conditions
Interventions
Traditional anesthesia group:Induction: propofol 2 mg/kg, alfentanil 10 µg/kg, maintenance: intravenous infusion of propofol 4-8 mg/(kg-h), alfentanil 0.2-1 mg/(kg-h). Intraoperative anesthesiologists
Opioid-sparing anesthesia group:Induction: propofol 2 mg/kg, esketamine 0.2 mg/kg, alfentanil 5 µg/kg, Maintenance: intravenous infusion of propofol 4-8 mg/(kg-h), alfentanil 0.2-1 mg/(kg-h). Intraope
Opioid-free anesthesia group:Flurbiprofen ester 50 mg and dexamethasone 5 mg were given in advance. induction: propofol 2 mg/kg, esketamine, and lidocaine 1.5 mg/kg. maintenance: intravenous infusion
Sponsors
The First Affiliated Hospital,Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Eligible subjects were between the ages of 18 and 70 years old, scheduled for painless hysteroscopic surgery at the First Affiliated Hospital of Zhejiang University School of Medicine, and had an American Society of Anesthesiologists (ASA) physical status of Class I-III.
Exclusion criteria
Exclusion criteria: Relevant to the subject: Hearing impaired unable to communicate; subjects with mental or neurological disorders. Lesion-Related: Subjects with clinically significant preoperative cardiovascular disease. Subjects in a pregnant state. Exclusion Criteria Related to Comorbid Medications Subjects with preoperative chronic pain or taking pain medication prior to surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative drug dosage;Number of times respiratory support was required intraoperatively;Postoperative pain visual analog score;Postoperative recovery room stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative subject satisfaction;Number of intraoperative body movements;Number of intraoperative body movements; | — |
Countries
China
Contacts
Public ContactShuhan Gu
The First Affiliated Hospital,Zhejiang University School of Medicine
Outcome results
None listed