proliferative diabetic retinopathy
Conditions
Interventions
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Observation group (Group A) : Patients with proliferative diabetic retinopathy (PDR) undergoing vitrectomy in the ophthalmology department of our hospital Control group: Group B (control group 1) : non-diabetic patients with non-vascular retinopathy (macular hole, macular anterior membrane, retinal detachment, retinal hiatus) who underwent vitrectomy in our ophthalmology department; Group C (control group 2) : non-vascular retinopathy patients with diabetes (macular hole, macular anterior membrane, retinal detachment, retinal hiatus) undergoing vitrectomy in the ophthalmology department of our hospital.
Exclusion criteria
Exclusion criteria: 1. History of ocular trauma; 2. Other eye diseases and surgical history; 3. Patients with abnormal coagulation function; 4. Have a serious systemic history, such as malignant tumors, autoimmune diseases; 5. Patients with unsatisfactory blood sugar control; 6. Patients with unsatisfactory blood pressure control; 7. History of use of vegetarian and systemic antibiotics or probiotics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| gut microbiome signatures;serum metabolomics ;vitreous metabolomics ; | — |
Countries
China
Contacts
Public ContactMing Zhang
West China Hospital, Sichuan University
Outcome results
None listed