Chronic hepatitis B
Conditions
Interventions
CHB patients who meet the criteria for ataxia:None
Sponsors
The First Affiliated Hospital of Naval Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Age >=18 years old, gender unlimited 2.The diagnosis of chronic hepatitis B is in accordance with the Chronic Hepatitis B Diagnosis and Treatment Guidelines (2022 edition). 3.HBsA<=1500Iu/ml 4. Agree to accept interferon therapy for "functional cure" 5. Agree to take an additional 5ml of peripheral blood on the basis of routine follow-up examination as needed for clinical research 6. With good compliance, can understand and sign informed consent
Exclusion criteria
Exclusion criteria: 1. Pregnancy or short-term pregnancy plan 2. A history of mental illness (a history of schizophrenia or severe depression), uncontrolled epilepsy 3.Decompensated cirrhosis 4.Uncontrolled autoimmune disease 5. Serious infections, retinal diseases, heart failure, chronic obstructive pulmonary disease and other underlying diseases 6. Acute and chronic infection with HCV, HDV, HEV and other hepatitis viruses 7.Combined with autoimmune diseases, HIV infection and other diseases that may affect the host immune status 8.Patients with previous interferon therapy and drug resistance 9. The researchers suggest that there may be patients with poor compliance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HBsAg;HBV DNA; | — |
Secondary
| Measure | Time frame |
|---|---|
| Alanine aminotransferase; | — |
Countries
China
Contacts
Public ContactLiang Xuesong
The First Affiliated Hospital of Naval Medical University
Outcome results
None listed