metabolic dysfunction-associated fatty liver disease
Conditions
Interventions
experimental group:A resistance exercise program will be implemented for the first 7 weeks, followed by an aerobic exercise program for the subsequent 7 weeks
control group:An aerobic exercise program will be implemented for the first 7 weeks, followed by a resistance exercise program for the subsequent 7 weeks.
Sponsors
Beijing Sport University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Sedentary lifestyle (weekly physical activity less than 90 minutes) 2. MRI-PDFF (Magnetic Resonance Imaging Proton Density Fat Fraction) >= 5%
Exclusion criteria
Exclusion criteria: 1. Exclusion if any of the following conditions apply: 2. Presence of unstable cardiovascular disease symptoms; 3. Excessive alcohol consumption (men >30 g/day, women >20 g/day); 4. Diagnosis of other liver diseases (e.g., viral hepatitis); 5. Current or history of malignancy (cancer); 6. Recent significant weight fluctuations (e.g., >5% body weight change within 3 months); 7. Failure to provide informed consent; 8. Any other conditions deemed by investigators to render participation in the study inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intrahepatic triglyceride; | — |
Secondary
| Measure | Time frame |
|---|---|
| alanine aminotransferase;aspartate aminotransferase;fasting glucose;fasting Insulin;homeostatic model assessment of insulin resistance;quantitative insulin sensitivity check index;total cholesterol;high-density lipoprotein cholesterol;low-density lipoprotein cholesterol;triglyceride;body weight;waist circumference;body mass index; | — |
Countries
China
Contacts
Public ContactRenjie Bing
Beijing Sport University
Outcome results
None listed