Acute postoperative chest pain
Conditions
Interventions
The group of bupivacaine liposomal:Thoracic paravertebral analgesia with liposomal bupivacaine
Sponsors
Beijing Chest Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1: American Society of Anesthesiologists (ASA) classification: I-III; 2: Age> 18; 3: There is no restriction on gender; 4: Undergoing elective thoracoscopic lobectomy under general anesthesia.
Exclusion criteria
Exclusion criteria: 1: Refusal to receive PVB or PCIA treatment; 2: Previous anatomical variation of the spine, history of chronic pain; 3: History of alcoholism, opioid abuse; 4: Those who are allergic to local anesthetics or are intolerant to general anesthesia; 5: Abnormal liver and kidney function and coagulation function; 6: Patients with severe cardiovascular and cerebrovascular diseases (myocardial infarction, atrioventricular block, etc.) or abnormal heart rhythm (heart rate100 beats/min, non-sinus heart rate); 7: Pregnant or lactating females, those who have a birth plan within half a year, and who are unwilling or unable to take effective contraceptive measures; 8: Those who are unable to cooperate with pain assessment, such as mental abnormalities or paresthesias; 9: The patient voluntarily requested to withdraw from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pharmacokinetic parameters of bupivacaine liposome population; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensory block extent;Current Perception Threshold;Pain Perception Threshold; | — |
Countries
China
Contacts
Public ContactLiu Wei
Beijing Chest Hospital Affiliated to Capital Medical University
Outcome results
None listed